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盐酸氨溴索预防胸部手术并发症的效果观察 被引量:4

Evaluation of the treatment effect of ambroxol hydrochloride in prevention of thoracic operation syndrome
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摘要 目的:探讨盐酸氨溴索预防胸部手术后并发症的临床应用。方法:将60例胸部手术的患者,分为氨溴索治疗组和安慰剂对照组,氨溴索治疗组于术前3日,手术当日,术后5日静脉滴注盐酸氨溴索;安慰剂对照组接受相同的胸外科常规治疗方案。结果:接受氨溴索治疗的患者与接受安慰剂治疗的患者相比,肺泡表面活性物质恢复更迅速,能够更早地恢复到正常的肺泡表面张力。结论:氨溴索可减少胸部手术围术期肺不张的发生和动脉低氧血症,对胸部手术后患者的肺功能保护起到了积极的作用。 OBJECTIVE To study the clinical application of ambroxol hydrochloride in the prevention of thoracic operation sydrome. METHODS A total of 56 patients were divided into therapeutic group and placebo group, the therapeutic group re ceived the drug treatment from three days before operation to five days after operation, the other groups just received conventional therapy. RESULTS Comparing this two groups. The mean operation time of the first group was significantly shorter than that in the second group.the convalescence of the alveolar surfactant was shorter. CONCLUSION The clinical application of ambroxol hydrochloride can reduce the incidence rate of atelectasis and hypoxemia, to the person who received thoracic operation, it plays an important role in protecting pulmonary function.
作者 张程
出处 《中国医院药学杂志》 CAS CSCD 北大核心 2009年第11期918-920,共3页 Chinese Journal of Hospital Pharmacy
关键词 胸部手术 并发症 盐酸氨溴索 ambroxol hydrochioride thoracic operation comnlications
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