摘要
目的:观察关节康治疗膝骨性关节炎的临床疗效。方法:选择肝肾亏虚,血脉不利证膝骨关节炎患者46例,随机分为2组。对照组24例给予塞来昔布治疗;治疗组22例在对照组治疗基础上加用关节康治疗。疗程36周。结果:2组疼痛计分、功能计分治疗4、12、36周与治疗前比较,差异均有显著性意义(P<0.05)。治疗36周时2组比较,差异有显著性意义(P<0.05)。2组总计分治疗4、12周与治疗前比较,差异有显著性意义(P<0.05);治疗12、36周时2组治疗比较,差异有显著性意义(P<0.05)。结论:塞来昔布短期内可以改善患者的关节功能,缓解疼痛;关节康对骨性关节炎患者短期内疗效并不突出,但随着随访时间的延长,患者可出现疗效上升的趋势;通过补肾活血中药配合塞来昔布取长补短,在临床中可取得满意疗效。
Objective:To observe the therapeutic effect of Guanjiekang for the treatment of knee osteoarthritis(KOA).Methods:Forty-six KOA patients with liver-kidney insufficiency and dysfunction of blood vessels were randomized into 2 groups:the control group received celecoxib, and the treatment group received celecoxib combined with Guanjiekang.The treatment lasted 36 weeks.Results:After treatment for 4,12 and 36 weeks,the scores of pain in knee joint and the knee function in the two groups differed from those before treatment(P<0.05),and the difference was significant between the two groups after treatment for 36 weeks(P<0.05).The total score in the two groups after treatment for 4 and 12 weeks differed from that before treatment(P<0.05), and the difference was significant between the two groups after treatment for 12 and 36 weeks(P<0.05).Conclusion:Celecoxib has a short-term effect on relieving join function and pain,and Guanjiekang has a long-term effect.Guanjiekang combined with celecoxib exerts a better effect than celecoxib or Guanjiekang alone.
出处
《新中医》
CAS
北大核心
2009年第6期59-60,共2页
New Chinese Medicine
