摘要
目的:评价Q值调整的个体化准分子激光角膜内磨镶术(LASIK)矫正高度近视的安全性、有效性和可预测性.方法:应用Oculyzer眼前节分析系统(Wavelight,Inc),Allegretto Wave Eye-Q准分子激光系统和F-CAT个体化切削手术程序,对42例(84眼)高度近视患者随机一眼选择Q值调整的个体化LASIK手术,作为对照另一眼选择标准的像差优化LASIK手术.随访6mo,评价手术后临床疗效.结果:Q值调整组和像差优化组术后第6mo①安全性:两组术后最佳戴镜矫正视力无下降2行及以上,下降1行的各仅为1眼.②有效性:术后裸眼视力分别为(5.09±0.03)和(5.05±0.20).术后视力5.0以上均为100%,5.1以上分别为57.1%和52.4%.③可预测性:术后平均等值球镜(显然验光)分别为(-0.02±0.56)D和(-0.09±0.49)D,在±0.75D以内均为100%,±0.50D以内分别为84.2%和83.6%.④术后Q值分别为(0.28±0.36)和(0.44±0.23),两者差异有显著性.结论:两组均有较高的安全性、有效性和可预测性.Q值调整的个体化切削术后角膜的非球面性更合理,远期疗效有待进一步随访和研究.
AIM： To evaluate the efficacy, safety and predicta- bility of Q-value adjusted customized laser in situ keratomileusis （LASIK） for high myopia and astigmatism using an Allegretto Wave Eye-Q platform. METHODS： Eighty-four high myopia eyes （from 42 patients） were enrolled in a controlled study, in which 42 eyes were randomly chosen to be treated with Q-value customized ablation （Q-value adjusted study group） and another eye of the same person was treated with standard Wavefront-optimized ablation （ control group）. The procedures for both groups were conducted with an Allegretto Wave Eye-Q excimer laser system. Q-value customized ablation was prepared with a scheimpflug topography with the Oculyzer anterior segment imaging system （Wavelight, Inc. ） and F-CAT ablation planning software. The efficacy, safety and predictability were evaluated for a period of 6 months following the surgery. RESULTS： The evaluation at 6 months showed the following results for the Q-value adjusted group and wavefront-optimized group： Safety： No eye lost more than 2 lines of best spectacle-corrected visual acuity （BSCVA） in either group and only 1 eye lost line of BSCVA ; Efficacy ： UCVA was （5.09 ±0.03 ） and （5.05 ±0.20）, with 5.0 or better in 100% in both groups, and 5.1 or better in 57.1% and 52.4%, respectively; Predictability： Postoperative mean spherical equivalent of the manifest refraction （SE） was （ - 0. 02 ±0. 56） D and （ -0.09 ±0.49 ）D, with all eyes within ＋ 0.75D of the intended correction, and 84.2% and 83.6% of the eyes within ± 0.50D of the intended correction, respectively; Q-value ： Postoperative Q-value for Q-value adjusted group was （0.28 ± 0.36）, which required significantly less oblation compared with that required in wavefront-optimized group （0.44 ±0.23 ）. CONCLUSION ： A 6-month follow-up indicates that both Q-value customized ablation and standard wavefront-optimized ablation LASIK surgeries show very good safety, efficacy and predictab
出处
《第四军医大学学报》
北大核心
2009年第10期940-942,共3页
Journal of the Fourth Military Medical University
