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益生菌对溃疡性结肠炎维持缓解的作用 被引量:13

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摘要 溃疡性结肠炎(ulcerative colitis,UC)是炎症性肠病在我国的主要发病形式,临床最常见的是复发和缓解交替。由于其发病机制不明,目前无明确根治措施,临床治疗以诱导和维持缓解为主,然而对于急性期患者,即使标准的维持治疗方案,疗效也不能令人满意,仅能将1年内复发率降为50%,且有部分患者不能接受长期应用5氨基水杨酸(5-ASA)类药物的不良反应。近年来,肠腔内源性微生物在炎症性肠病发病中的地位获得越来越广泛的认同,已经有较多研究关注益生菌在活动期炎症性肠病中的作用,我们对益生菌维持缓解作用进行了随机对照观察,评价其作为维持治疗方案的疗效。
出处 《中华消化杂志》 CAS CSCD 北大核心 2009年第5期341-342,共2页 Chinese Journal of Digestion
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参考文献17

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