摘要
目的:建立宫炎平分散片的质量标准。方法:采用薄层色谱(TLC)法对方中地稔、两面针、五指毛桃进行定性鉴别;用高效液相色谱法测定制剂中没食子酸的含量。结果:TLC斑点清晰、分离度好、专属性强。没食子酸进样量在0.14648～2.9296μg范围内与峰面积积分值呈良好线性关系(r=0.9997);平均回收率为99.89%,RSD=2.53%(n=6)。结论:所建标准可用于宫炎平分散片的质量控制。
OBJECTIVE： To establish the quality standard of Gongyanping dispersible tablets. METHODS： Melastoma dodecandrum, Zanthozylum nitidum and Fieus simplicissima in the formulation was identified by TLC, and the content of gallic acid in gongyanping dispersible tablets was determined by HPLC. RESULTS： The TLC spots were clear, well- isolated and distinctive. The linear range of gallic acid was 0.146 48--2.929 6μg（r ： 0.999 7） and its average recovery was 99.89% （RSD = 2.53%, n = 6）. CONCLUSION： The established quality standard can be used for the quality control of Gongyanping dispersible tablets.
出处
《中国药房》
CAS
CSCD
北大核心
2009年第15期1170-1171,共2页
China Pharmacy
