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双酚A雄性生殖毒性研究进展 被引量:11

Research Advance in Reproductive Toxicity of Bisphenol A to Male
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摘要 目前,对环境雌激素双酚A(BPA)是否诱发雄性生殖毒性仍有争议。笔者就国内外关于BPA雄性生殖毒性的研究进行了综述。文献报道表明,BPA虽然胚胎毒性不明显,但对雄性动物具有生殖毒性,而且睾丸和前列腺为主要靶器官,即使低剂量暴露BPA亦可出现毒性效应。 It was argued whether bisphenol A (BPA) can induce reproductive toxicity to male, so in the present paper the recently published articles on the reproductive toxicity induced by BPA to male were reviewed. It was indicated that BPA has no obvious embryotoxicity,but BPA can directly induce the reproductive toxicity to male reproductive system,and the testis and prostate were the main target organs of BPA. Even low level BPA exposure could produce toxic effects.
出处 《环境与健康杂志》 CAS CSCD 北大核心 2009年第5期467-469,共3页 Journal of Environment and Health
关键词 双酚A 雄性 生殖毒性 Bisphenol A Male Reproductive toxicity
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  • 1石峻岭,杨水莲,肖国兵,郑力行,周志俊.普通人群血清双酚A水平的测定[J].环境与职业医学,2004,21(3):190-193. 被引量:16
  • 2Kinnberg K, Toil G. Effects of estrogenic and antiandrogenic compounds on the testis structure of the adult guppy (Poecilia reticulata). Ecotoxicol Environ Saf, 2003,54( 1 ): 16-24. 被引量:1
  • 3Bhat HK, Calaf G, Hel TK, et al. Critical role of oxidative stress in estrogen-induced carcinogenesis. Proc Natl Acad USA, 2003,100(7):3913-3918. 被引量:1
  • 4Tam NN, Ghatak S, Ho SM, et al. Sex hormone-induced alterations in the activities of antioxidant enzymes and lipid peroxidation status in the prostate of Noble rats. Prostate, 2003,55 (1): 1-8. 被引量:1
  • 5Lascombe I, Beffa D, Ruegg U, et al. Estrogenic activity assessment of environmental chemicals using in vitro assays: Identification of two new estrogenic compounds. Environ Health Perspect, 2000, 108(7):621-629. 被引量:1
  • 6Karels AA, Manning S, Brouwer TH, et al. Reproductive effects of estrogenic and antiestrogenic chemicals on sheephead minnows. Environ Toxicol Chem, 2003,22(4): 855-865. 被引量:1
  • 7Yadetic F, Arukwe A, Goks0yr A, et al. Induction of hepatic estrogen receptor in juvenile Atlantic salmon in vivo by the environmental estrogen, 4-nonylphenol. Sci Total Environ, 1999, 233 (1-3): 201-210. 被引量:1
  • 8Khrana S, Ranmal S, Ben-Jonathan N, et al. Exposure of Newborn male and female rats to environmental estrogens: delayed and sustained hyperoprolactinemia and alterations in estrogen receptor expression. Endocrinology, 2000,141 ( 12): 4512--4517. 被引量:1
  • 9Wong JS, Gill SS. Gene expression changes induced in mouse liver by di (2-ethylhexyl) phthalate. Toxicol Appl Pharmacol, 2002,185 (3):180-196. 被引量:1
  • 10Takao T, Nannamiya W, Nazarloo HP, et al. Exposure to the environmental estrogen bisphenol A differentially modulated estrogen receptor-alpha and -beta immunoreactivity and mRNA in male mousetestis. Life Sci, 2003,72( 10): 1159-1169. 被引量:1

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