摘要
目的总结肿瘤介入治疗后疼痛特点,探讨其合理镇痛治疗原则。方法235例肿瘤患者共接受了489次介入治疗,统计疼痛发生率,分析疼痛的相关因素。重度疼痛患者使用强阿片类药物止痛,观察疼痛变化趋势和镇痛药的不良反应。21例次使用了超前镇痛。结果术后24小时内出现疼痛289例次,疼痛发生率60.1%,重度疼痛221例次,45.1%。介入后疼痛与栓塞剂、靶血管水平、多脏器同时治疗、合并基础慢性癌痛密切相关。单独使用即释强阿片类药物,可使52.1%重度疼痛患者在一天内明显缓解,其余重度疼痛者需联合使用强阿片类药物,3天以上可明显缓解。强阿片类药物治疗介入后疼痛未发现严重不良反应。超前镇痛可减轻介入后疼痛程度。结论介入治疗后疼痛是急性疼痛,以三阶梯止痛原则为指导,首选使用强阿片类镇痛药镇痛,安全、有效。超前镇痛应有良好效果。
Objective： To summarize the characteristic of the pain after interventional therapy of malignant tumors, discuss the principle of antalgic therapy in reason.Methods：489 times of interventional therapy were performed in 235 patients of malignant tumors,The incidences of pain and the correlative factors were analyzed.The patients with severe pain were treated with strong opioid analgesics,the tendency of changes of pain and side effects of analgesics were observed .21 patients were treated with analgesics in advance. Results：Within 24 hours after interventional therapy,the incidences of pain were 60.1%（289cases）, the incidences of severe pain were 45.1%（221cases）.The pain after interventional therapy was related with embolus, target vessel, multiple organ therapy and choronic cancer pain. Within a day,The incidences of obvious remission of severe pain were 52.1% with strong opioid analgesics .Combination with strong opioid analgesics ,the else＇s severe pain became obvious remissived after three days.There were no severe side effects of strong opioid analgesics in all of cases. Analgesics in advance can alleviate pain after interventional therapy. Conclusion： The pain after interventional therapy is acute.Under the guidance of three steps analgesic ladder,first choice of strong opioid analgesics,the analgesics effect after interventional therapy is safe and effective. Analgesics in advance have good effects on the pain after interventional therapy.
出处
《当代医学》
2009年第5期46-48,共3页
Contemporary Medicine
关键词
恶性肿瘤
介入治疗
疼痛
镇痛治疗
malignant tumors
interventional therapy
Pain, antalgic therapy
