摘要
目的观察综合性重症监护病房(ICU)患者下呼吸道标本非发酵菌的构成及耐药情况,为临床治疗提供科学依据。方法回顾性调查我院2006年11月1日～2008年11月1日期间综合性重症监护病房(ICU)下呼吸道标本中非发酵菌的构成及耐药率。结果共分离革兰氏阴性杆菌466株,其中非发酵菌298株,占63.95%(298/466);非发酵菌主要为铜绿假单胞菌、鲍曼不动杆菌、嗜麦芽窄食假单胞菌,其中部分非发酵菌为多重耐药菌(MDR),甚至为泛耐药菌(PDR)。结论综合性重症监护病房(ICU)下呼吸道标本中非发酵菌的所占比例较大,耐药率高,应定期监测其细菌构成及耐药率,为临床治疗提供指导。
Objective To investigate the non--fermentative bacterial distribution and drug--resistance regarding lower respiratory tract in patients in intensive care unit（ICU）and provide theoretical bases of rational usage of antibiotics for the clinic. Methods The distribution and drug--resistance of strains from patients in lower respiratory tract in ICU collected from November of 2006 to November of 2008 were studied retrospectively. Results Among 466 gram--negative bacillus isolated from lower respiratory tract in patients in ICU, the non--fermentative bacteria covered63. 95% （298/466）, pseudomonas aeruginosa,stenotrophomonas maltophilia and ancinetobacter baumanni were the main non--fermentative bactrial,some of them were multi drug--resistant and pan drug--resistant. Conclusions The isolation rate of non-- fermenters are increasing in lower respiratory tract in patients in ICU in recent years,periodic survelliance should be done to/earn the drug resistance and bacterial distribution in ICU and instruct the clinic to use antibiotics rationally.
出处
《齐齐哈尔医学院学报》
2009年第5期531-532,共2页
Journal of Qiqihar Medical University
关键词
重症监护病房
下呼吸道
非发酵菌
耐药性
Intensive care units Lower respiratory tract Nonfermentative bacterial Antibiotic resistance
