摘要
目的分析高脂血症性急性胰腺炎的临床特征，并探讨其治疗策略。方法采用回顾性临床研究方法，分析2003年1月至2007年12月住院的44例高脂血症性急性胰腺炎（HLP）患者的临床特征，并与同期60例非HLP患者做对照。结果HLP组超重（或肥胖）、高血糖、脂肪肝以及高血压病史比例分别为81．8％、59．1％、54．5％和68．2％，显著高于对照组的16．7％、16．7％、13．3％和16．7％（P〈0．05或〈0．01）；而HLP组胆系结石占13．6％，显著低于对照组的60．0％（P〈0．05）。两组酗酒者所占比例无显著差异。HLP组Ranson评分、CT严重指数（CTS!）、并发症发生数分别为3．15±0．07、4．46±2．58和3．2±1．7，均高于对照组1．62±0．22、2．62±1．90和0．9±1．2（P〈0．05或〈0．01），而HLP组血淀粉酶为（580±221）mmol／L，显著低于对照组的（1360±472）mmol／L（P〈0．01）。HLP组血三酰甘油（TG）值与Ranson积分之间存在直线相关（r=0．77，P〈0．05），对照组TG值与Ranson积分之间无直线相关性（r=0．17，P〉0．05）。结论HLP与代谢综合征关系密切。血TG水平与HLP病情严重程度呈正相关。
Objective To analyze the clinical features of acute hyperlipidemic pancreatitis, and to investigate the therapeutic strategies. Methods In this retrospective study, 44 patients with hyperlipidemic pancreatitis admitted to our hospital from January 2003 to December 2007 were enrolled, 60 patients with acute pancreatitis of other etiologies were enrolled as the control group. Results The proportions of patients with overweight or obesity, hyperglycemia, fatty liver and hypertension were 81. 8%, 59. 1%, 54. 5% and 68.2%, respectively; these were significantly higher than those in control group, which were 16.7%, 16.7%, 13.3% and 23.3%, respectively （ P 〈 0.05 or 〈 0.01 ）. The proportion of patients with lithiasis was lower in HLP group than that in control group （13.6% vs 60.0% , P 〈 0.05 ）. There was no difference in the proportions of patients with chronic alcoholism between two groups. The Ransom score, CTSI, complications in HLP group were 3.15 ± 0.07, 4.46 ± 2.58 and 3.2 ± 1.7, respectively ; these parameters were significantly higher than those in control group, which were 1.62 ± 0.22, 2.62 ± 1.90 and 0.9 ± 1.2 （ P 〈 0.05 or 〈 0.01 ）. The level of serum amylase in HLP group was 580 ± 222 mmol/L, which was significantly lower than that of control group （1361 ±472 mmol/L, P 〈 0.01 ）. The triglyeeride （TG） level was linearly correlated with Ranson score in HLP group （ r = 0.77, P 〈 0.05 ） , but there was no linear correlation between TG level and Ranson score in the control group. Conclusions There was a close relationship between HLP and metabolic syndrome. Serum TG was positively correlated with the severity of HLP.
出处
《中华胰腺病杂志》
CAS
2009年第2期89-91,共3页
Chinese Journal of Pancreatology
