摘要
目的探讨老年急性胰腺炎(AP)患者胰腺外损害的临床特征。方法回顾性分析215例急性胰腺炎的病历资料,其中老年组124例,非老年组91例,分析其病因、胰腺外损害的临床特征以及与预后的关系。结果老年AP患者以胆源性病因为主,占71.0%,而非老年AP患者以非胆源性病因较多见,占50.50%(P<0.005)。68.4%的AP患者合并有胰腺外损害,81.5%的老年AP患者并有胰腺外损害,明显高于非老年组(50.5%)(P<0.005)。老年组常见胰腺外受损部位依次为肝脏(70.2%),呼吸道(25.0%)和胃肠道(8.9%)。肾功能不全、心功能不全、胰性脑病及DIC等虽然较少见,但主要见于老年患者。27.4%的老年AP患者合并2种或以上器官受损,与非老年组比较差异有显著性(P<0.01)。老年组伴有胰腺外损害的AP患者其复发率、转重症发生率均高于非老年组,平均住院时间比非老年组长,两组比较差异有显著性(P<0.05)。结论急性胰腺炎是一种可累及多系统的疾病,老年AP患者容易合并胰腺外损害,合并胰腺外损害的老年患者预后较差。
Objective To study the clinical features of extra-pancreatic impairment in elder patients with acute pancreatitis （AP）. Methods Medical history materials of 215 patients with AP were studied retrospectively. Among these patients, 124 were ≥ 60 years old（ elder group） and 91 were 〈 60 years old （non-elder group）. The etiology, extra-pancreastic impairment and prognosis of these patients were analyzed. Results Biliary disease was the most common cause of AP in elder group （71.0%）. While in non-elder grou, non-biliary diseases were more common （50.5 % ）（ P 〈 0.005）. Patients with extra-pancreatic impairment accounted for 68.4% in 81.5 % patients of elder group and 50.5 % patients of non-elder group of all the patients. Extra-pancreatic impairment happened. In elder group, liver malfunction was the most frequent extra-pancreatic impairment （70.2 % ）, followed by respiratiory （25.0 % ） and gastroenteric impairment （ 8.9 % ）. Renal malfunction, heart malfunction, pancreatic encephalopathy and DIC occurred mainly in elder group. Thirty four （27.4%） patients of elder group had two or more extra-pancreatic impairment. The recurrence rate, the seriousness rate of elder group were higher than that of non-elder group（ P 〈 0.05 ）. The hospitalization duration of elder group was longer than that of non-eledr group （ P 〈 0.05 ）. Conclusion AP is a disease affecting multiple system and organs. The elder AP patients were liable to extra-pancreatic impairment, and had serious prognosis.
出处
《胃肠病学和肝病学杂志》
CAS
2006年第2期147-149,共3页
Chinese Journal of Gastroenterology and Hepatology
关键词
胰腺炎
损害
预后
Pancreatitis
Impairment
Prognosis
