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内镜经鼻蝶入路手术治疗大型垂体腺瘤 被引量:18

Treatment of Pituitary Macroadenoma through Endoscopic Endonasal Transsphenoidal Approach
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摘要 背景与目的:对于大型垂体腺瘤,传统的开颅和经蝶入路手术均难以全切,本文探讨内镜经鼻蝶入路切除大型垂体腺瘤的手术技术。方法:回顾性分析2000年9月~2005年12月间治疗的大型垂体腺瘤患者39例,术前均行头CT、MRI及内分泌学检查,手术采用内镜经鼻蝶入路肿瘤切除术。结果:本组患者无手术死亡,肿瘤全切除23例(60.0%),近全切除14例(35.9%),部分切除2例(5.1%)。术后随访6~24个月,症状和内分泌学指标均有所改善,肿瘤复发2例。结论:内镜经鼻蝶手术是治疗大型垂体腺瘤微创、安全的方法。 BACKGROUND & OBJECTIVE: In treatment of pituitary macroadenoma, total resection is difficult through traditional transcranial and transsphenoidal approach. This article is to discuss the operative techniques of endoscopic transsphenoidal surgery for resection of pituitary macroadenoma. METHODS: From September 2000 to December 2005, 39 cases of pituitary macroadenoma were treated by endoscopic endonasal transsphenoidal surgery. All the cases were evaluated by MRI, CT scan, and endocrinological examination before operation. RESULTS: There was no surgical death. The tumors were totally removed in 23 cases (60.0%), sub-totally removed in 14 cases(35.9%) and partly removed in 2 cases(5.1%). All patients were followed up from 6 to 24 months with improved clinical symptoms and endocrinological status. Tumor recurrence was found in 2 cases within follow-up period. CONCLUSION: The endoscopic endonasal transsphenoidal surgery is minimally invasive and safe in treatment of pituitary maeroadenoma.
出处 《中国神经肿瘤杂志》 2009年第1期22-24,共3页 Chinese Journal of Neuro-Oncology
关键词 垂体腺瘤 内镜 经鼻蝶手术 Pituitary macroadenoma Endoscope transsphenoidal surgery
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