摘要
目的:探讨黄芪熬液对离体蟾蜍心脏收缩力和心率的影响.方法:采用斯氏蛙心插管法,在保持总量为1.0ml的情况下,分别以不同浓度的黄芪熬剂对离体的蟾蜍心脏进行灌流,经BL-420F生物机能实验系统记录心肌的收缩活动.结果:本实验观察用低浓度(0.002g.ml-1-0.010g.ml-1)黄芪熬液灌流离体蟾蜍心脏时,可使其心肌收缩力、心率明显增加,t检验表明心肌收缩力、心率均变化显著(p<0.05)或极显著(p<0.01);用高浓度(0.02g.ml-1-0.06g.ml-1)黄芪熬液灌流离体蟾蜍心脏时,则抑制心肌收缩力和心率,t检验表明心肌收缩力和心率变化极显著(p<0.01).结论:黄芪熬液对离体蟾蜍心脏起双重调节作用.
Objective： To study the effects of astragalus＇s decoction on the contractility and heart rate of isolated heart of toad. Method ： To adopt the method of Straw to record the result of the experiment though BL - 420F intelligent bio - date display and process system in the situation of keeping the total AD amount as 1.0ml. Result： The result shows that the astragalus＇s decoction can improve or restrain the myocardial contraction force and the heart rate. Under lower concentration （0.002g. ml^-1 - 0.010g.ml^-1 ）, the strength and the frequency of the heart has been strengthened, T test shows that the strength and frequency of the heart increased distinctly or extremely （P 〈 0.05 Or P 〈 0.01） . Under higher concentration （0.02 g. ml^-1 - 0.06g. ml^-1 ）, the strength and the frequency of the heart has been restrained, T test shows that the strength and the frequency of the heart decreased extremely （P 〈 0.01） . Conclusion： these results showed astragalus＇s decoction had two- side regulation to the heart.
出处
《怀化学院学报》
2009年第2期60-62,共3页
Journal of Huaihua University
关键词
黄芪熬液
蟾蜍
斯氏蛙心插管法
心肌收缩力
心率
Astragalus＇s decoction
Toad
Method of Straw
Myocardial contraction force
Heart rate
