Wnt5a对非小细胞肺癌细胞侵袭能力的影响
被引量：2
摘要
Wnt5a是Wnt家族中的重要成员之一，在肺的发育及其分化过程中起着重要作用，并可能参与非小细胞肺癌（non—small cell-lung cancer，NSCLC）的发生与发展。我们通过构建Wnt5a基因正义及RNAi重组质粒并将其导入NSCLC细胞株H157和A549，观察Wnt5a基因表达的变化对NSCLC细胞侵袭及迁移等行为的影响，探讨Wnt5a在NSCLC发生与发展中的作用及机制。
出处
《中华结核和呼吸杂志》
CAS
CSCD
北大核心
2009年第4期298-300,共3页
Chinese Journal of Tuberculosis and Respiratory Diseases
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