摘要
The Prins reaction between most olefins and formaldehyde shows non-stereospecificity and region selectivity. All the additions of halostyrene, cyclopentene and other olefms are conducted through open ion mechanism. However, the Prins reaction of cyclohexene with water or acetic acid as solvent gives the trans-product stereospecifically with excellent yield. It is considered that the Prins reaction of cyclohexene different from the addition of other
基金
The note is a related work of the research subiects supported by the National Natural Science Foundation of China