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组织因子凝血途径抑制物 被引量:2

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摘要 近年来国外对组织因子凝血途径抑制物(Tissue factor pathway inhibitor,TFPI)研究报道较多。已成为一个热点。本文拟就其性质、作用机理、应用等做一综述。 1 TFPI的性质 早年在1947年Thomas和Schneide就各自独立报道了在对TF诱导DIC动物模型中。
出处 《血栓与止血学》 1995年第1期30-32,共3页 Chinese Journal of Thrombosis and Hemostasis
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参考文献12

  • 1Girard TJ,er al.Structure of the human LACI gene. Journal of Biological Chemistry . 1991 被引量:1
  • 2Wun T-C,et al.Cloning and characterization of a cDNA coding for the LACI shows that it consists of three tandem Kunits-type inhibitory domains. Journal of Biological Chemistry . 1988 被引量:1
  • 3Wesselschmidt R,et al.Structure requirements for TFPI interactions with factor Ⅹ a and heparin. Blood . 1992 被引量:1
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  • 6Sanne V,et al.Comparison of different glycosamino-glycans with reapect to their capacity for binding of TFPI. Thrombosis and Haemostasis . 1993 被引量:1
  • 7Wildgooes P,et al.Evidence that the c-terminus of TFPI is essential for its interaction with lipoproteins. Thrombosis and Haemostasis . 1991 被引量:1
  • 8Wesselschmidt R,et al.TFPI: The carboxyl terminus is required for optimal inhibition of factor Ⅹ a. Blood . 1992 被引量:1
  • 9Giard TJ,et al.Functional significance of the kunitz type inhibitor domains of LACI. Nature . 1980 被引量:1
  • 10Sandset PM,et al.Heparin induces release of extrinsic coagulation pothway inhibitor.Thronb. Resource . 1988 被引量:1

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