摘要
目的:观察外用中药生肌膏和玉红膏作用的创伤渗出液中巨噬细胞结构和功能的变化,探讨“偎脓长肉”作用机制。方法:改良 Schilling 技术获取家兔创伤渗出液,观察渗出液中巨噬细胞形态,异质性,Fc 受体和氧化代谢功能。结果:生肌膏组和玉红膏组巨噬细胞多且多见游走型,异质性荧光染色多为Ⅰ、Ⅱ型细胞。Fc 受体和氧化代谢功能与对照组比较均有显著性差异(P<0.01)。结论:外用中药作用的创伤渗出液中含有大量形态和功能活跃的巨噬细胞,这应是外用中药“偎脓长肉”加速创伤修复的重要基础。
Objective:To study the structure and function of the macrophages of the wound transudate and mechaniam of Weinong Zhangrou of the external application Chinese herbal medicine Shengji ointment and Yuhong ointment.Methods: The rabbits wound transudate was collected with modified Schilling stainless steel tubes.Macrophages morphology,het- erogenity,Fc receptor and oxidation-metabolic function of wound transudate were studied.Results:The experiment re- suits indicated that Shengji ointment group and Zhangrou ointment group bad many motility type macrophages and type Ⅰ,Ⅱ macrophages with the heterogentic dye in wound transudate.The activity of Fc receptors and oxidation-metabolic function activity were much better than those in control group.Conclusion:The groups treated with Chinese herbal oint- ment had a large number of active macrophages in wound transudate,that might be the basal action of Weinong Zhangrou improving the reparing ability of wound healing.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
1998年第S1期344-346,409-410,共5页
Chinese Journal of Integrated Traditional and Western Medicine
