摘要
目的探讨神经节细胞胶质瘤的临床表现、影像学特点、治疗方法及预后。方法回顾性分析18例神经节细胞胶质瘤患者的临床表现、影像学特点、治疗方法及随访结果。结果所有患者均行手术治疗,肿瘤全切16例,次全切除2例,复发1例,再次手术治疗。所有病例术后均随访2～6年,16例恢复正常工作和学习;14例术后癫痫缓解,3例需要服用药物控制癫痫,1例3年后复发,二次手术后恢复正常。结论神经节细胞胶质瘤预后相对良好,手术是目前其主要的治疗方法,早期发现,早期治疗,有助于提高患者生存质量和减少复发率。
Objective To explore clinical manifestations, neuroimaging characteristics, treatment and prognoses in the patients with intracranial gangliogliomas. Methods The clinical data of 18 patients with intracranial gangliogliomas who underwent neurosurgery in our department from January, 2000 to December, 2005 were analyzed retrospectively. All the patients were followed up from 2 to 6 years. Results There was recurrent tumor, which was totally resected by the re-operation, in 1 of 16 patients who received total resection of the tumors. The postoperative radiotherapy was performed in 2 patients who received subtotal resection of the tumors. The following-up showed that of 18 patients, 16 returned to normal work and study, 1 had light hemiplegia and 1 had ataxia. Epileptic remitted in 14 patients after the operation, epileptic seizure was controlled by antiepileptic drugs in 3 patients and there was good recovery in 1 patients undergoing re-operation for the recurrent tumor. Conclusions The patient with ganglioglioma has a relatively favorable prognosis. The surgical resection is main method to treat gangliogliomas. The importance of early diagnosis and total resection of gangliogliomas should be emphasized.
出处
《中国临床神经外科杂志》
2009年第3期150-152,共3页
Chinese Journal of Clinical Neurosurgery
