摘要
目的:研究B超在陡脉冲治疗兔肝肿瘤中的作用及治疗的有效性.方法:建立兔VX2肝脏肿瘤细胞实体瘤模型,随机分为治疗组及对照组,分别予以陡脉冲及假性治疗.治疗过程中用B超定位及实时监测,治疗后1,4,7,14d分别B超及镜下观察治疗靶区.结果:在陡脉冲治疗过程中,B超能起到很好的引导定位及监测作用;镜下观察治疗靶区呈广泛性凝固性坏死.结论:陡脉冲可致肿瘤细胞发生不可逆性损伤,B超作为一种辅助手段,能运用于陡脉冲治疗及术后监测中.
Objective： To study the effect of ultrasound in the process of treating liver cancer of rabbit with steep pulse and the validity of the therapy. Methods： A rabbit liver tumor model was constructed and the rabbits were divided into the control group and the experimental group, which were subjected to steep pulse treatment and fake treatment, respectively. The ultrasound was used in plotting and real time monitoring. The target volume was observed by ultrasound and microscope 0, 1, 4, 7 and 14 days later. Results： Ultrasound played a good role in plotting and monitoring in the process of steep pulse therapy. Extensive coagulation necrosis was noticed in microscopic examination. Conclusions; Steep pulse can lead to irreversible damage to cancer cells. As a supplementary means, ultrasound can be used in the steep pulse treatment and in post-operation monitoring.
出处
《西南大学学报（自然科学版）》
CAS
CSCD
北大核心
2009年第1期111-115,共5页
Journal of Southwest University(Natural Science Edition)
基金
国家自然科学基金资助项目(50637020)
关键词
B超
陡脉冲
肝癌
ultrasound
steep pulse
liver cancer
