摘要
目的通过Cockcroft—Gauk公式评估老年人肾小球滤过率（GFR）值变化，分析影响老年人肾功能的相关因素。方法选择本院内科住院患者145例作为患者组，年龄60～86岁，无慢性肾脏病；选择门诊健康体检者100例作为对照组，年龄60～82岁。通过测定血清肌酐、血浆白蛋白、身高及体质量等计算GFR值，比较不同年龄组间肾功能差异。结果GFR值随年龄增加而下降，对照组与患者组中各年龄组比较均有显著性差异；血肌酐对照组与〉70～80岁组、〉80岁组比较有显著性差异；血浆白蛋白60～70岁组与〉80岁组比较有显著性差异。结论老年人肾功能随年龄增加而降低，同时患有慢性疾病、血浆白蛋白水平降低、营养不良为其加重因素。
Objective It is to evaluate the change of GFR value of elderly patients with Cockcroft - Gault equation to analyze the factors which affect the renal function in the persons. Methods 145 patients in 60 - 86 years old without chronic renal diseases in our hospital were selected. GFR was evaluated by measuring serum creatinine, body height and weight, and plasm albumin to compare the difference in renal function and factors which affect the renal function with different age patients and with contrast group of 100 healthy people in 60 - 82 years old. Results GFR value was decreased with aging, and the difference was significant between contrast group and patient group of different age. The difference in level of serum creatinine was significant in 70 - 80 years and over 80 years groups compared with contrast group. There was significant difference in plasm albumin between 60 - 70 years and over 80 years groups （P 〈 0. 005）. Conclusion The renal function was decreased with aging in elderly patients, even worse in patients with chronic diseases, low level of plasm albumin and malnutrition.
出处
《现代中西医结合杂志》
CAS
2009年第10期1085-1086,共2页
Modern Journal of Integrated Traditional Chinese and Western Medicine
关键词
肾小球滤过率
老年人
身高
体质量
血肌酐
Glomerular filtration rate
elderly people
body height
weight
serum creatinine
