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产前感染和炎症与新生儿支气管肺发育不良的研究进展 被引量:7

Progress in association between antenatal infection, inflammation and bronchopulmonary dysplasia of newborn
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摘要 新生儿支气管肺发育不良(BPD)可导致婴幼儿反复住院,严重影响儿童体格增长和神经系统的发育,病死率较高。产前感染与BPD的发生关系密切,主要病原体为B族溶血性链球菌、解脲脲原体等。细胞因子如白细胞介素-6、白细胞介素-β、转化生长因子-β等在肺部炎症反应中起着非常重要的作用。弹性蛋白、转化生长因子哉肺泡上皮细胞、血管内皮生长因子等参与肺泡发育过程。产前感染和炎症是BPD发生的危险因素,但如何导致BPD发生尚需深入研究。
出处 《国际儿科学杂志》 2009年第2期143-146,共4页 International Journal of Pediatrics
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参考文献30

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