摘要
目的观察高压氧在血管性痴呆治疗中的临床疗效和作用机制。方法将确诊的血管性痴呆82例病人随机分为两组：对照组42例，应用丹参20ml加入0．9％NS 250ml中静滴，脑复康50ml静滴，1次／d，14d为1个疗程，共2疗程；高压氧组40例，给予高压氧治疗，1次／d，12d为1个疗程，共2个疗程。两组治疗前后均进行认知障碍和痴呆程度评分，以简易智力状态检查量表（MMSE）和日常生活能力量表（ADL）为症状改善评价指标。结果两组病人治疗前后，高压氧组MMSE评分变化差异有统计学意义（P〈0．05），对照组MMSE评分变化差异无统计学意义（P〉0．05），高压氧组ADL评分差异有统计学意义（P〈0．05），对照组ADL评分变化差异无统计学意义（P〉0．05）。两组有效率比较差异有统计学意义（P〈0．01），高压氧组（89．7％）优于对照组（47．1％）。结论高压氧对血管性痴呆有康复作用。
Objective To observe the clinical effect and the mechanism of hyperbaric oxygen（HBO） in the treatment of vascular dementia （VD）. Methods Eighty-two patients with the VD were divided into two groups at random：the control group （the pure drug group,42cases, ）and the experiment group（ the HBO group,40 cases）. All of patients were tested by the cognitive impairment and dementia＇ s rating and the evaluation index of the symptoms improvement were valued by the Mini-mental state examination （MMSE） and annual daily living （ADL） before and after the treatment. Results The comparison of the data before and after treatment showed, MMSE score changes in HBO group had significant differences （P〈0.05）, there were no significant difference （P 〉0.05）in the control group, ADL score had significant difference in the HBO group （P 〈 0.05 ）, there was no significant difference in the ADL score changes of the control group （P〉0.05）. Conclusion HBO play the rehabilitation role in the vascular dementia.
出处
《中国临床新医学》
2009年第2期127-129,共3页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
关键词
高压氧治疗
血管性痴呆
疗效
Treatment of hyperbaric oxgen（HBO）, Vascular dementia（VD）
Therapeutic effect
