摘要
目的通过收集急性一氧化碳中毒迟发性脑病（DEACMP）患者的临床资料，分析影响其预后的因素。方法回顾性分析2003年2月至2007年5月在我科住院的35例DEACMP患者临床资料，6个月-3年后随访其恢复情况，总结出性别、年龄、基础疾病、吸烟、急性期是否高压氧（HBO）治疗、昏迷时间、中毒时间、假愈期、最重时日常生活能力量表（ADL）评分、并发症、HBO治疗次数及神经节苷脂（GM-1）的应用等12个可能影响此病预后的因素。用SPSS10．0软件对数据作X^2检验。结果中毒时间、最重时ADL评分、并发症、HBO治疗次数对预后有一定影响，其中最重时ADL评分及并发症对预后有较大影响；而其余因素对预后影响不大。结论中毒时间越长、最重时ADL评分越低及病程中出现并发症的患者预后较差，疾病治疗过程中应注意加强患者的护理，减少并发症的发生，并积极进行HBO治疗。
Objective To explore the prognostic factors of delayed encephalopathy after carbon monoxide poisoning（DEACMP）. Methods Thirty-five patients diagnosed as DEACMP in our hospital from February 2003 to May 2007 were observed. After follow-up visiting, factors of age, sex, fundament diseases, smoking,hyperbaric oxygen treatment（HBOT） in acute stage,unconsciousness time,intoxication time,fake-cure stage,danger-activity of daily living scale （ADL） scores, complications, HBOT frequency and ganglioside administration were analyzed, respectively. Chi-Square test was used to analyse those data by SPSS10. 0 software. Results Intoxication time, danger-ADL scores, complications and HBOT frequency had effected on the recovery of DEACMP（P 〈0.05 ） , especially danger-ADL scores and complications （P〈0.01）. The other factors did not have significant difference（P〉0.05 ）. Conclusions Longer intoxication time,less danger-ADL scores and more complications lead to slower recovery. Nursing care and HBO treatment should be reinforced.
出处
《中华航海医学与高气压医学杂志》
CAS
CSCD
2008年第3期152-155,共4页
Chinese Journal of Nautical Medicine and Hyperbaric Medicine
关键词
急性一氧化碳中毒
迟发性脑病
高压氧
预后
日常生活能力量表
Carbon monoxide poisoning
Delayed encephalopathy
Hyperbaric oxygen
Prognosis
Activity of daily living scale
