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嗅鞘细胞移植治疗脊髓损伤的研究进展 被引量:12

An update of repairing spinal cord injury by olfactory ensheathing cells
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摘要 脊髓损伤的治疗一直是医学界的难题。脊髓损伤后神经元轴突再生困难,同时神经胶质瘢痕阻碍再生轴突的通过。嗅鞘细胞是一种特殊的神经胶质细胞,具有中枢神经系统(CNS)星形胶质细胞和外周雪旺氏细胞的特性,许多基础与临床研究发现嗅鞘细胞是神经系统中具有促进神经轴突再生,引导轴突正确生长的独特细胞,取得了一定的成果,为脊髓损伤的修复带来了希望。 The treatment of spinal cord injury is always a stubborn problem for neurosurgeons because nerve cell cannot regenerate and the glia scar can prevent the axonal regeneration. Olfactory ensheathing cells (OECs)is a kind of especial glia cell, which possesses the character of horizontal cell of central nervous system and schwann cell. Many foundational and clinical studies showed that the olfactory ensheatbing cellscan promote axonal regeneration and prove axonal growth, some progress is made and this is bringing hope for treatment of spine injury.
出处 《中国骨伤》 CAS 2009年第1期68-71,共4页 China Journal of Orthopaedics and Traumatology
基金 上海市教委科研基金资助(编号:05cz12)
关键词 嗅鞘细胞 移植 脊髓损伤 综述文献 Olfactory ensheathing cells Transplantation Spinal cord injuries Review literature
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参考文献33

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