摘要
目的应用速度向量成像（VVI）技术评价不同程度缺血心肌局部功能的变化。方法引）例冠心病患者，在VVI条件下经胸采集心尖四腔观、两腔观和长轴观超声心动图图像。根据冠状动脉（冠脉）造影结果将所有心肌节段分为5组：0级组，冠脉无狭窄；1级组，冠脉狭窄〈50%；2级组，冠脉狭窄50％～74％；3级组，冠脉狭窄75％～99%；4级组，冠脉完全闭塞。测量各组心肌节段收缩期应变（ε）、应变率（SRs），舒张早期应变率（SRe）、舒张晚期应变率（SRa）及SRe／SRa。结果①与0级组比较，1级组SRe、SRe／SRa，2～4级组SRs、SRe、SRe／SRa，2级组和4级组ε均降低（P〈0.05）；②1～4级组间比较，2级组ε、SRs、SRa低于1级组（P〈0.05），3级组ε、SRe、SRa高于2级组（P〈0．05），1级组与3级组比较差异无统计学意义；4级组ε、SRs、SRe低于i级组，SRe低于2级组．ε、SRs、SRe低于3级组（P〈0.05）。结论随冠脉狭窄程度加重，缺血心肌早期先后出现舒张和收缩功能异常，并出现明显减低后回升再降低的双向变化。
Objective To assess ischemic myocardial regional function of different coronary atherosclerosis using velocity vector imaging（VVI）. Methods Two-dimensional images of apical four, two-chamber and long-axis view were obtained in 50 patients with coronary artery disease. All segments of the left ventricle were divided into 5 groups：group 0 with no coronary artery stenosis,group l with stenosis 〈50%,group 2 with stenosis 50% to 74% ,group 3 with stenosis 75% to 99% and group 4 with a completely occluded coronary artery. The segmental myocardial systolic peak strain（ε）,systolic strain rate（SRs）, early diastolic strain rate（SRe）, late diastolic strain rate（SRa） and their ratio（SRe/SRa） were analyzed with VVI offline software. Results （1）Compared with group 0,SRe and SRe/SRa of group 1, SRs, SRe, SRe/SRa of group 2 - 4, ε of group 2 and group 4 decreased significantly（P〈0.05）. （2）In the comparison of four ischemic groups,ε,SRe,SRa of group 3 were markedly higher than those of group 2, while ε,SRs,SRa of group 2 were lower than those of group 1 （ P〈0.05） ;for group 4,ε,SRs,SRe were lower than those of group 1 ,SRe was lower than that of group 2,and ε,SRs,SRe were lower than those of group 3 （ P〈0.05）. Conclusions In the process of coronary atherosclerosis, myocardial diastolic and systolic dysfunction occurred early and orderly,and has a bidirectional change：decreased firstly, then increased and decreased at last.
出处
《中华超声影像学杂志》
CSCD
北大核心
2009年第1期1-3,共3页
Chinese Journal of Ultrasonography
基金
基金项目：山东省科技攻关项目（2006GG2202039）及医学科技攻关项目（2005HZ048）
关键词
超声心动描记术
心室功能
左
心肌缺血
速度向量成像
Echocardiography
Ventricular function, left
Myocardial ischemia
Velocity vector imaging
