摘要
目的研究氦氖激光照射对缺血性脑血管疾病疗效的影响。方法190例缺血性脑血管疾病患者随机分为常规组65例,治疗组63例,对照组62例。分别在治疗前及治疗后1个月进行血液流变学、超氧化物歧化酶(SOD)和丙二醛(MDA)水平及血清BDNF含量检测,同时进行临床疗效观察,与常规组和对照组比较,观察氦氖激光照射对缺血性脑血管疾病血液流变学、抗氧化能力、脑源性营养因子(BDNF)和临床疗效的影响。结果与常规组和对照组比较,治疗后治疗组全血黏度高低切变值和血浆黏度明显改善(P<0.01),血清SOD活力增高(P<0.01),MDA含量显著降低(P<0.01),血清BDNF含量明显增加;临床疗效比较,治疗组明显优于常规组和对照组。结论氦氖激光照射能促进神经功能恢复,是治疗缺血性脑血管疾病的理想方法之一。
Objective To study the effects of He-Ne laser irradiation for ischemic eerebrovascular disease. Methods One hundred and ninty patients with cerebrovascular ischemia were divided into routine therapy group of 65 cases and He-Ne laser therapy group of 63 cases, and control group of 62 eases randomly. The hemorheology and the level of super oxidedismutase （SOD） and malondialdehyde （MDA） and brain-derived neurotrophic factor（BDNF） in blood serum were measured. At the same time. the clinical efficacy was compared before the treatment and one month later. Compared with routine therapy group and control group, the effect of He-Ne laser irradiation therapy on the hemorheology, anti-oxidizing power, BDNF and clinical efficacy in ischemic cerebrovascular disease were analyzed. Results Compared with routine treatment group and control group, the whole blood viscosity shear value and plasma viscosity and BDNF were improved distinctly （P〈0.01）. In addition the level of SOD increased and MDA decreased significantly（P〈0.0l）. Comparison of clinical efficacy, it was better than conventional group and control group. Conclusion He-Ne laser irradiation can promote neurological recovery. It will be the most ideal medicament of curing cerebral isehemia.
出处
《中国实用神经疾病杂志》
2009年第1期1-5,共5页
Chinese Journal of Practical Nervous Diseases
基金
河南省濮阳市科技攻关项目(080560)
