摘要
在免疫监视的Logistic肿瘤生长动力学模型中引入关联的乘性白噪声,并考虑抗肿瘤体系的免疫系统激活阈值存在差异,对上述动力学生长方程进行数值仿真计算.发现噪声关联强度能够调节抗肿瘤体系个体的免疫效果,但调节的结果存在差异;噪声关联强度λ的取值存在一个最佳区间,在该区间内更多的抗肿瘤体系个体能实现最大免疫效果.
We introduced two correlated Gaussian multiplicative white noises into the Logistic growth model for an anti-tumor system subject to immune surveillance.Considering various active thresholds to initiate the immunity of the anti-tumor system,we made numerical simulations to investigate how the intensity λ of two correlated white noises influences the immune effect of an anti-tumor system.Our numerical results reveal that the correlation intensity λ has an optimal value,at which the anti-tumor system will achieve functionally the best immunity.
出处
《物理学报》
SCIE
EI
CAS
CSCD
北大核心
2009年第1期97-101,共5页
Acta Physica Sinica
基金
国家自然科学基金(批准号:30770629)资助的课题~~
