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急性桐油中毒大鼠实验模型的建立及其形态学改变 被引量:5

Morphologic Changes of Rat Model of Moentjang Tina
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摘要 模拟人类桐油中毒的方式,以不同剂量桐油灌喂大鼠,制作大鼠急性桐油中毒的模型。发现:不同剂量的桐油可引起不同程度的肺脏、肝脏、肾脏和心脏的损伤。而且,各脏器的损伤程度随着灌喂剂量的增加而增加。结果提示急性桐油中毒可以导致全身多个器官的损伤。 at model of Moentjang tina was produced by imitating Moentjang tina of human beings with different dose of Tung oil (Aleuriter fordii), which had made 55 people poisoned. The result showed that different pathological changes, such as interstitial edema of lung, hydropic degeneration of proximal tubule, fatty degeneration of hepatocyte and loose cytoplasm of myocardium, happened in groups of different dose of Tung oil, and that the severity of injury paralleled somewhat to the amount of oil used. The experiment indicates that Tung oil can cause comprehensive injuries of different organs.
出处 《首都医科大学学报》 CAS 1998年第1期5-8,共4页 Journal of Capital Medical University
关键词 桐油中毒 实验模型 形态学 病理机制 Moentjang tina rat model morphologic changes
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