摘要
目的:观察依达拉奉联合前列腺素E1治疗急性脑梗死的疗效。方法:选择我院神经内科住院50例发病72 h以内的急性脑梗死患者,随机分为两组,应用依达拉奉联合前列腺素E1为试验组,胞二磷胆碱联合前列腺素E1为对照组,治疗前后两组对照进行神经功能缺损评定。结果:试验组神经功能缺损程度明显改善,显效率和总有效率均高于对照组(P<0.05)。结论:依达拉奉联合前列腺素E1能有效改善急性脑梗死的神经功能缺损,具有良好的安全性,无明显不良反应。
Objective：To evaluate the efficacy of edaravone combined with prostaglandin E1 in treatment of acute cerebral infarction. Methods： A randomized and controlled trial was performed in 50 patients with acute cerebral infarction. Patients were enrolled within 72 h of onset, and randomly allocated to edaravone （n = 24） or control group （n = 26）. Before and after treatment, the neurological deficits were assessed. Results： The neurological function impairment was significantly improved after edaravone treatment as compared with the control. There was significant difference between the two groups （P 〈0.05）. Conclusion： Edaravone combined with prostaglandin E1 can effectively and safely improve the neurological dysfunction after acute cerebral infarction without obvious adverse reactions.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2008年第23期2059-2060,共2页
Chinese Journal of New Drugs
关键词
依达拉奉
前列腺素E1
急性脑梗死
疗效
edaravone
prostaglandin E1
acute cerebral infarction
efficacy
