摘要
目的：了解福建晋江水中肠杆菌科细菌的种类及其对抗菌药物的耐药性。方法：用采样器采集晋江江水10个点,水样经增菌培养和细菌分离,用常规方法和微生物分析仪进行细菌鉴定,药敏试验采用纸片琼脂扩散法。结果：从江水中分离出肠杆菌科细菌144株,其中大肠埃希菌47株（32.6%）、肠杆菌属细菌31株（21.5%）、奇异变形杆菌29株（20.1%）、克雷伯菌属细菌23株（16.0%）、沙雷菌属细菌8株（5.6%）、成团泛菌4株（2.8%）和弗劳地枸橼酸杆菌2株（1.4%）。药敏试验结果显示,130株肠杆菌科细菌对亚胺培南和头孢哌酮/舒巴坦的耐药率为0%,对左氧氟沙星、阿米卡星、奈替米星、头孢他啶和头孢噻肟的耐药率为3.2%～9.7%,对头孢呋辛、环丙沙星和氨曲南的耐药率为17.4%～38.7%,对氨苄西林和头孢唑啉的耐药率为51.6%～95.7%。结论：晋江水中肠杆菌科细菌对多种抗菌药物产生了一定的耐药性,开展江水细菌调查及耐药性监测,对于防治江水细菌感染和控制耐药菌株播散都具有重要意义。
Objective：To investigate the species of Enterobacteriaceae and its antimicrobial resistance from water of Jinjiang River in Fujian.Methods：The water specimens were collected from ten different water areas of Jinjiang River and were cultured,isolated and identified.Microbial sensitivity tests were performed with the Kirby-Bauer method.Results：Among 144 strains bacteria isolated from the water specimens,47（32.6%） were Escherichia coli,31（21.5%） were Enterobacter,29（20.1%） were Proteus mirabilis,23（16.0%） were Klebsiella,8（5.6%） were Serratia,4（2.8%） were Pantoea agglomerans,2（1.4%） were Citrobacter freundii.The drug susceptibility reports showed that the bacterial resistance rates to imipenem and cefoperazone/sulbactam were 0%,to levofloxacin,amikacin,netilmicin,ceftazidime and cefotaxime were 3.2%～9.7%,to cefuroxime,ciprofloxacin and aztreonam were 17.4%～38.7%,to ampicillin and cefazolin were 51.6%～95.7%.Conclusion：It is very important to carry out surveillance of bacterial resistance for prevention and therapy of Enterobacteriaceae infection in Jinjiang River.
出处
《中国卫生检验杂志》
CAS
2008年第12期2677-2678,共2页
Chinese Journal of Health Laboratory Technology
基金
全军医药卫生科研基金课题(06D004)
关键词
水
肠杆菌科
细菌
耐药性监测
Water
Enterobacteriaceae
Bacteria
Surveillance of bacterial resistance
