摘要
目的:研究泽漆Euphorbia helioscopia的多酚类成分。方法:用Diaion HP-20,Toyopearl HW-40,硅胶等柱色谱技术,结合制备液相和重结晶方法进行分离纯化,根据化合物的理化性质和光谱数据鉴定结构。结果:分离并鉴定了10个化合物,即没食子酸(1),没食子酸甲酯(2),连苯三酚(3),(-)-莽草酸-4-O-没食子酸酯(4),(-)-莽草酸-5-O-没食子酸酯(5),1-O-没食子酰基-2,3-六羟基联苯二甲酰基-α-D-吡喃葡萄糖(6),l,3,6-三-O-没食子酰基-β-D-吡喃葡萄糖(7),l,2,3,6-四-O-没食子酰基-β-D-吡喃葡萄糖(8),间二苯酚(9),没食子酸-4-O-(6'-O-没食子酰基)-β-D-吡喃葡萄糖(10)。结论:化合物3～10为首次从该植物中分离得到。
AIM： To study the polyphenol constituents from Euphorbia helioscopia. METHODS： The compounds were isolated and purified by Diaion HP-20, Toyopearl HW-40, silica gel column chromatography, preparative liquid chromatography, and recrystallization. Their structures were identified on the basis of spectral data and physiochemical properties. RESULTS： Ten compounds were isolated and elucidated as： gallic acid （1）, methyl gallate （2）, pyrogallol（3）, （-）-shikimic acid-4-O-gallate （4）, （-）-shikimic acid-5-O-gallate （5）, 1-O-galloyl-2, 3-HHDP-a-D-glucose （6）, 1, 3, 6-tri-O-galloyl-β-D- glucose （7）, 1, 2, 3, 6-tetra-O-galloyl-β-D-glucose（8）, resorcinol （9）, gallic acid-4-O-（6＇-O-galloyl）-fl-D-glucose （10）. CONCLUSION： Compounds 3-10 have been isolated from this plant for the first time.
出处
《中国天然药物》
SCIE
CAS
CSCD
北大核心
2009年第1期37-39,共3页
基金
supported by the Key Project of Chinese Ministry of Education (DF2003078)~~
关键词
大戟属
泽漆
多酚类
Euphorbia
Euphorbia helioscopia
Polvohenols
