摘要
目的:研究单麻叶千里光Senecio cannabifolius var.integrilifolius(Koidz.)Kitam.地上部分的化学成分,为阐明其有效成分提供科学依据。方法:采用silicagel、SephadexLH-20及RP18等柱层析色谱方法进行分离纯化,并根据理化性质和光谱数据鉴定其结构。结果:分离得到9个化合物,分别鉴定为:柳杉酚(1)、浙贝素(2)、消旋丁香脂素(3)、齐墩果烷(4)、1,4-苯二酚(5)、2,5-二羟基苯乙酸乙酯(6)、对羟基苯乙酰胺(7)、槲皮素(8)及金丝桃苷(9)。结论:化合物1和2为首次从该属植物中分离得到,化合物1～9均为首次从该植物中分离得到。
AIM： To investigate the chemical constituents of Senecio cannabifolius var. integrilifolius （Koidz.） Kitam. METHODS： Compounds were isolated and purified by various chromatography techniques and their structures were elucidated by physicochemical properties and spectroscopic data. RESULTS： Nine chemical constituents were isolated and identified as sugiol （1）, zhebeiresinol （2）, lirriodendrin （3）, oleanane（4）, 1,4-benzenediol（5）, ethyl 2,5-dihydroxy benzeneacetate（6）, p-hydroxyphenylacetylamide（7）, quercetin（8） and hyperoside（9）, respectively. CONCLUSION： Compounds 1 and 2 were isolated from the genus for the first time. Compounds 1-9 were isolated from this plant for the first time.
出处
《中国天然药物》
SCIE
CAS
CSCD
北大核心
2009年第1期28-30,共3页
基金
supported by National Natural Science Foundation of China (No 30530840, 30572222, 30701104)
National Basic Research Program of China (No 2006CB504704)~~
关键词
单麻叶千里光
化学成分
Senecio cannabifolius var. integrilifolius
Chemical constituents
