摘要
目的:分析我院中药注射剂不良反应(ADR)的发生规律及特点,推动临床合理用药。方法:对我院2004～2007年报告的167例中药注射剂ADR,利用MicrosoftExcel电子表格进行频数分析。结果:导致ADR的中药注射剂涉及17个品种,其中用于治疗突发性耳聋或缺血性心脑血管疾病的活血化瘀类发生率最高,尤以注射用葛根素(20.4%)和己酮可可碱氯化钠注射液(19.8%)最高。最常见的ADR为神经系统损害(30.4%),其次为皮肤及其附件损害(23.3%)。结论:建议改进中药注射剂生产工艺,提高其质量,并在应用中注意辨证施治,同时加强ADR监测,以期最大限度地减少其ADR的发生。
OBJECTIVE： To analyze the rules and characteristics of the occurrence of the adverse drug reactions（ADRs） associated with traditional Chinese medicine injections so as to promote the rational drug use.METHODS： A total of 167 ADR cases induced by traditional Chinese medicine injections collected in our hospital from 2004 to 2007 were analyzed by means of Microsoft Excel .RESULTS： The 167 ADR cases were caused by a total of 17 kinds of traditional Chinese medicine injections. The drugs used for the sudden deafness or ischemic cardiovascular and cerebrovascular diseases showed the highest incidence of ADRs, much as in the use of Puerarin for injection（20.4% ） and Pentoxifylline sodium chloride injection（19.8% ） .The most common presentation of the ADRs was lesion of nervous system（30.4% ） followed by the lesion of skin and accessories（23.3% ）. CONCLUSION： To decrease the incidence of ADRs to a large extent, it is advisable to improve the preparation techniques and promote the quality of the traditional Chinese medicine injections, attach great importance to the principle of dialectic treatment in practice meanwhile enhancing the ADR monitoring.
出处
《中国药房》
CAS
CSCD
北大核心
2009年第3期225-227,共3页
China Pharmacy
关键词
中药注射剂
药品不良反应
分析
Traditional Chinese medicine injection
ADRs
Analysis
