摘要
目的:探讨慢性肾衰患者的铁参数和贫血的关系。方法:测定正常对照组与慢性肾衰﹙CRF﹚组的血红蛋白(Hb)、血清铁(SI)、总铁结合力(TIBC)、运铁蛋白饱和度(TS)以及血清铁蛋白(FER)指标,并进行t检验和相关性分析。结果:慢性肾衰血红蛋白(Hb)、血清铁(SI)、总铁结合力(TIBC)、运铁蛋白饱和度(TS)以及血清铁蛋白(FER)与健康组相比,差异有统计学意义(P<0.05),铁蛋白(FER)与血清铁(SI)和血红蛋白(Hb)存在负相关。结论:铁原料的缺乏是肾性贫血的一个不可忽略的因素,总铁结合力(TIBC)不升反降,考虑主要与肾功能损害时转铁蛋白的丢失过多有关;肾性贫血的患者存在铁代谢紊乱及铁超负荷的倾向。
Objective： To study the relation between values of iron and renal anemia. Methods： HB, SI, TIBC TS, FER were detected in normal group and chronic renal failure respectively. Results： There were statistical difference between normal group and chronic renal failure group for RBC, HB, SI, TIBC, TS, FER; There were negative association between normal group and chronic renal failure group, SI and HB ,FER and HB. Conclusion： There are metabolism disorder of iron in chronic renal failure.
出处
《中国医药导报》
CAS
2008年第36期84-85,共2页
China Medical Herald
