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MTA家族与乳腺癌关系的研究进展 被引量:1

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摘要 MTA基因家族是一类重要的肿瘤转移相关基因,它们主要参与组蛋白去乙酰基酶(nucleosome remodeling deacetylase,NuRD)的组成。组蛋白去乙酰基酶具有核小体重塑活性,对基因转录有抑制作用,并能通过调节雌激素通路途径促进乳腺肿瘤的侵袭和转移,故与乳腺癌关系密切,是研究乳腺癌转移机制和治疗的新靶点。
出处 《临床外科杂志》 2008年第12期848-850,共3页 Journal of Clinical Surgery
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参考文献23

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