摘要
目的探讨肺功能对咳嗽变异型哮喘(cough variant asthma,CVA)诊断的指导意义。方法回顾性分析门诊慢性咳嗽和典型哮喘患者共176例的肺功能,慢性咳嗽患者分成CVA组和支气管激发试验阴性的对照组。结果CVA组和对照组肺通气功能多正常,支气管激发试验后CVA组最大用力呼气中段流速占预计值百分比(FEF25～75%)显著下降(P<0.01)。结论气道高反应性和小气道通气障碍为CVA和典型哮喘肺功能的共同特征,支气管激发试验有助于CVA诊断。
Objective To investigate the guiding significance of pulmonary function for the diagnosis of cough variant asthma （CVA）. Methods The pulmonary functions of 63 patients with typical asthma and 113 patients with chronic cough,including 57 patients with CVA and 56 patients with negative results of bronchial provocation test （control subjects）, were analyzed retrospectively. Results The pulmonary functions of CVA patients and control subjects were normal. FEF25-75% after bronchial provocation test significantly decreased in CVA patients （P 〈 0.01 ）. Conclusion Bronchial hyperreactivity and abnormal small airway function are the common features in patients with CVA and typical asthma. Bronchial provocation test can help diagnose CVA.
出处
《中国医科大学学报》
CAS
CSCD
北大核心
2008年第5期704-705,共2页
Journal of China Medical University
关键词
肺功能
咳嗽
哮喘
咳嗽变异型哮喘
支气管激发试验
pulmonary function
cough
asthma
cough variant asthma
bronchial provocation test
