摘要
目的调查广州地区不同人群女性泌尿生殖道沙眼衣原体(CT)感染情况,分析CT感染的危险因素。方法由医护人员组成性病艾滋病高危人群干预队,为目标人群提供性病防治知识讲座、问卷调查,发放健康处方和安全套,采集生殖道拭子用于萘瑟氏淋球菌(GC)、CT、解脲/人型支原体(UU/MH)等的常规检测。结果共问卷调查788人,对715人采集了宫颈拭子。CT总感染率为10.5%(75/715),其中流动人口育龄妇女、妇科门诊就诊者、暗娼的CT感染率分别为6.4%(15/234),11.1%(31/279),14.4%(29/202),各组间差异有统计学意义(P<0.05)。CT合并GC、UU/MH、单纯疱疹病毒Ⅱ型(HSV-2)、粘液脓性宫颈炎(MPC)感染者分别为5.3%、57.3%、36.0%、32.0%。暗娼中CT合并GC、HSV-2、MPC感染者分别为10.3%、51.7%、27.6%。CT感染与20岁以前发生性行为、未婚、配偶从事商业服务业、中重度宫颈炎以及每周性生活频率超过3次等5个因素有关。固定人群因素后发现,首次性生活年龄越早、口服避孕药为危险因素。结论性工作者是性病行为干预的重点,减少性生活频率,加强青少年禁欲宣传有助于减少CT感染的流行。
Objective To investigate the prevalence of Chalmydia trachomatis （CT） and risk behavioral factor among different female population groups in Gunagzhou. Methods Professional STD/AIDS intervention team was organized to provide STD/AIDS prevention service for target female population. Structured questionnaires were used to collect demographic and behavioral information of the subjects under study, and clinical and gynecologic examinations were performed to detect their clinical signs of STIs. Blood samples to test antibodies to syphilis and HSV/HIV. Vaginal discharge smears were tested for Trichomonas vaginalis （T. vaginalis）, Candida albican and Bacterial vaginalis （BV） . Cervical swabs were tested for Neisseria gonorrhoea （ N. gonorrhoea）, Mycoplasma and Chlamydia trachomatis （ C. trachomatis） . Results A total of 788 females participated in the study and of them 715 were sampled. The total prevalence of C. trachomatis among the target females was 10.4 % , and 6.4 % , 11.1% and 14.5 % for migrant female subpopulation, visitors to gynecologic clinics and female sex workers, respectively. Significant difference existed in CT prevalence rates among the three female population groups （P〈 0.05）. Co-infections in CT-infected females were also common. 5.3 % of them were infected with GC, 57.3 % with UU/MH,36 % with HSV-2 and 32 % with MPC. Among female sex workers, 10.3 % of persons infected with CT were co-infected with GC,65.5 % with UU/MH, 51.7 % with HSV-2 and 27.6 % with MPC. Independent risk factor included age of first sex debut under 20 years of age, being unmarried, mid to severe cervicitis, their husbands being engaged in commercial business and sex more than 3 times per week, while adjusted risk factors were oral contraceptive druge and age of first sex debut under 20 years of age if female group was taken into account alone, Conclusion STD/HIV behavior intervention should focus on sex workers, decreasing sex frequency per week and abstinence promotion may help to prevent C. trachomat
出处
《中国艾滋病性病》
CAS
2008年第6期606-608,共3页
Chinese Journal of Aids & STD
基金
卫生局科研立项资助(2006YB143)
广东省科委立项资助项目(2006B35901017)
广东省卫生厅立项项目(A2007545)
关键词
沙眼衣原体
危险因素
Chlamydia trachomatis
Investigation
Female
Risk factors
