摘要
目的探讨免疫荧光病理检验的敏感性在狼疮性肾炎(LN)诊断中的意义。方法采用直接免疫荧光法对262例LN患者肾活检组织进行免疫病理分析。结果IgG、IgA、IgM、C1q、C3均阳性者(满堂亮)在Ⅱ型LN中占44.83%,Ⅲ型中占50.00%,Ⅳ型中占76.09%,Ⅴ型中占67.65%。结论"满堂亮"现象在Ⅳ型、Ⅴ型LN中最多见,是特征性的病理表现,提高"满堂亮"阳性百分率对LN的诊断具有重要意义。
Objective To investigate the diagnostic significance of sensitivity of immunofluorescence pathological test for lupus nephritis（LN）.Methods Immunopathological data of 262 patients with LN diagnosed by renal biopsy were analyzed with direct immunofluorescence.ResultsThe percentage of positive result of all 5 antibodies（IgG,IgA,IgM,C1q and C3） was 44.83% in typeⅡ of LN,50% in type Ⅲ of LN,76.09% in type Ⅳ of LN,and 67.65% in type Ⅴ of LN,which was remarkably higher than that of the literatures.Conclusion The positive result of all 5 antibodies was seen mostly in type Ⅳ and Ⅴ of LN and was a specific pathological manifestation.Improving the sensitivity of immunofluorescence pathological test is of impotance in the diagnosis of LN.
出处
《江苏医药》
CAS
CSCD
北大核心
2008年第12期1196-1197,共2页
Jiangsu Medical Journal
关键词
免疫荧光病理检验
狼疮性肾炎
Immunofluorescence pathological test
Lupus nephritis
