摘要
目的:探讨低场MRI、超声及分子生物学对子宫腺肌症的临床诊断价值。方法:经手术病理证实的子宫腺肌症患者45例(研究组),子宫肌瘤36例(对照组)。所有患者术前行超声(经腹和经阴道途径)和低场(0.23T)MRI检查及血清CA125、CA153和CA199测定。分析各项检查方法(或指标)诊断的敏感性、特异性及准确性。结果:MRI检查诊断子宫腺肌症的敏感度为95.56%,特异度为100%,符合率为97.53%;经阴道超声分别为80.0%、88.89%和83.95%;经腹部超声为68.89%、83.33%和75.31%;血清CA125为46.67%、88.89%和65.43%;CA153为33.33%、94.44%和60.49%;CA199为15.56%、97.22%和51.85%。结论:MRI是诊断子宫腺肌症最有价值的检查手段;分子生物学检查方面,血清CA125测定优于CA153和CA199,可作为诊断子宫腺肌症的筛选检查方法。
Objective：To assess the clinical value of low field magnetic resonance imaging,sonography and molecular biology in the diagnosis of uterine adenomyosis. Methods： Low field MRI, sonography （transabdominal and transvaginal sonography） and testing of serum of CA125 ,CA199 and CA153 levels were carried out in 45 patients confirmed pathologically as uterine adenomyosis and 36 patients with leiomyoma after operation. The sensitivity, specificity and accuracy of each examination were analyzed. Results： The sensitivity, specificity and accuracy of low field MRI were 95. 56%, 100% and 97.53% ;those of TVS were 80.0%,88.89% and 83.95% ;those of TAS were 68.89% ,83.33% and 75.31% ;those of serum CA125 levels were 46.67% ,88.89% and 65.43% ;those of serum CA153 levels were 33.33%,94.44% and 60.49% ; and those of serum of CA199 levels were 15.56 %, 97.22 % and 51.85 %. Conclusion： MRI is the best technology in diagnosis of uterine adenomyosis, serum CA125 levels testing is better than CA153 and CA199 and can be done during initial screening of women with possible adenomyosis.
出处
《放射学实践》
2008年第11期1245-1248,共4页
Radiologic Practice
