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再生障碍性贫血患者血管生成与表皮生长因子的表达和意义

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摘要 再生障碍性贫血(AA)的发病机制极其复杂,至今尚未完全明确,其中微循环障碍是其重要发病机制之一。血管内皮生长因子(VEGF)是一种多功能的生长因子,能促进内皮细胞增殖和血管生成、增加血管通透性。表皮生长因子(EGF)是一种有效的促分裂素,能促进上皮细胞的增生、成熟、分化。对VEGF、EGF的早期研究主要集中在实体肿瘤,其能诱导血管形成,从而促进肿瘤的生长和转移。
出处 《中华血液学杂志》 CAS CSCD 北大核心 2008年第11期778-780,共3页 Chinese Journal of Hematology
基金 基金项目:江苏省兴卫工程医学重点人才资助项目(RC2007084) 江苏省六大人才高峰资助项目
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