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肝泰片质量标准研究

Study on the Quality Standard of Gantai Tablets
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摘要 目的建立肝泰片质量标准。方法对珠子草、甘草进行薄层鉴别研究,并用高效液相色谱(HPLC)法测定制剂中没食子酸的含量。结果薄层图谱斑点清晰,阴性对照无干扰。没食子酸在4.16~41.6μg浓度范围内与峰面积呈线性关系,平均回收率为100.31%,RSD为0.69%(n=5)。结论结果准确,重复性好,可用于该制剂的质量控制。 Objective To establish the quality standard of Gantai tablets. Methods Phyllanthus niruri Linn and Radix et Rhizoma Glycyrrhizae were identified with thin - layer chromatography. The content of gallic acid in Gantai tablets was determined by HPLC. Results Gallic acid had good linear relationship within the range of 4. 16 - 41.6 μg. The average recovery was 100.31% ,RSD =0.69%. Conclusion The results determined by the quality standard are accurate and repeatable. It can be used for the quality control of Gantai tablets.
出处 《时珍国医国药》 CAS CSCD 北大核心 2008年第11期2736-2738,共3页 Lishizhen Medicine and Materia Medica Research
关键词 肝泰片 质量标准 没食子酸 高效液相色谱 Gantai tablets Quality standard Gallic Acid HPLC
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