期刊文献+

转化生长因子-β_1在冠心病中的研究进展 被引量:9

下载PDF
导出
摘要 转化生长因子-β(TGF-β)是许多具有共同生物学特性的信号分子组成的大家族,称为TGF-β超家族(transforming growth factor-β superfamily),TGF-β1是其中一员,其参与冠状动脉粥样硬化的形成和狭窄、心肌梗死后重塑、细胞凋亡等过程,是冠心病领域研究的热点,但在冠心病过程中的作用尚未完全阐明,仍有争议。本文对近年来国内外研究文献加以综述,以便对TGF-β1做更深入研究,对其在冠心病中的作用有更新的认识.为冠心病发生发展机制的探讨、临床治疗提供新的思路。
出处 《实用医学杂志》 CAS 2008年第21期3779-3781,共3页 The Journal of Practical Medicine
基金 上海市教委博士点基金赞助项目(编号:200782)
  • 相关文献

参考文献18

  • 1Grainger D J, Kemp P R, Metcalfe J C, et al. The serum concentration of active transforming growth factor-beta is severely depressed in advanced atherosclerosis [J]. Nat Med, 1995,1 ( 1 ) : 74-79. 被引量:1
  • 2Djurovic S, Thelle D S, Ringstad J, et al. Altered serum concentrations of TGF- betaland Lp (a)lipoprotein and their correlation in patients with first acute myocardial infarction [ J ]. Nutr Metab Cardiovasc Dis, 1996,9 (5) : 250-254. 被引量:1
  • 3Batuman O, Go D, Clark L T, et al. Relation between cytokine levels and coronary artery disease in women [J]. Heart Dis, 2001,3(2) :80-84. 被引量:1
  • 4Os I, Djurovic S, Seljeflot I, et al. Transforming growth factor (TGF)-betal inversely related to vascular cell adhesion molecule-lin post-menopausal women with coronary artery disease. A possible mechanism for the putative cardioprotective role of TGF-betal [J]. Intern Med, 2002,251 (3) : 223-227. 被引量:1
  • 5Zhang X L, Topley N, Ito T, et al. IL-6 regulation of TGF-(beta) receptor compartmentalization and turnover enhances TGF-beta;signalling [J]. Biol Chem, 2005,280(13) : 12239-12245. 被引量:1
  • 6Argmann C A, Van Den Diepstraten C H, Sawyez C G, et al. Transforming; growth factor-β1 inhibits macrophage cholesteryl ester accumulation induced by native and ox-idized VLDL remnants [J]. Arterioscler Throm Vase Biol, 2001,21 (12):2011- 2018. 被引量:1
  • 7Zuckerman S H, Panonsis C, Evans C. TGF-beta reduced binding of high-density lipoproteins in marine macrophages and macrophage derived foam cells [J]. Atherosclerosis, 2001,155( 1 ) : 79-85. 被引量:1
  • 8Minami M, Knme N, Kataoka H, et al. Transforming growth factor-beta ( 1 ) increases the expression of lectin-like oxidized low-density lipoprotein receptor-1 [J]. Biocchem Biophys Res Common, 2001,272(2) :357-361. 被引量:1
  • 9Lindner V. Vascular repair processes mediated by transforming growth factor- beta [J]. Z kardiol, 2001,90 (suppl 3): 17-22. 被引量:1
  • 10Siow R C, Mallawaarachchi C M, Weissberg P L. Migration of adventitial myofibroblasts following vascular balloon injury: insights from in vivo gene transfer to rat carotid arteries [J]. Cardiovasc Res, 2003,59(1) :212-221. 被引量:1

同被引文献84

引证文献9

二级引证文献30

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部