摘要
目的探讨伽玛刀对小儿血管网状细胞瘤术后残留的治疗作用。方法回顾性分析9例小儿血管网状细胞瘤术后残留行伽玛刀治疗的临床资料，其中等剂量曲线范同平均50％，周边剂量平均18Gy，肿瘤中心剂量平均36．5Gy。结果9例患儿随访时间12－48个月，6例患儿肿瘤缩小50％以上，临床症状和体征得到明显改善；1例患儿无变化并再次行伽玛刀治疗；2例患儿肿瘤进行性增大．其中1例第二次伽玛刀治疗，1例第二次行开颅手术治疗。结论伽玛刀对小儿血管网状细胞瘤术后残留的治疗是一种安全、有效的方法，但要严格掌握适应证。
Objective To assess the therapeutic effect of gamma knife radiosurgery for residual tumors after surgical resection of hemangioblastoma in children. Methods The clinical data were retrospectively analyzed in 9 children who received gamma knife radiosurgery for the residual tumors after a previous surgery for hemangioblastoma resection. Results The 9 children were followed up for 12-48 months, and 6 children showed a tumor volume reduction by over 50% with obviously improved clinical symptoms. One child showed no response to the treatment and received a second gamma knife radiosurgery. In 2 children, the tumor volume increased progressively after the radiosurgery, and a second radiosurgery was performed in 1 case and open surgery in the other. Conclusion Gamma knife radiosurgery is safe and effective for treatment of the residual tumors in children with previous surgical resection of hemangioblastoma.
出处
《中华神经医学杂志》
CAS
CSCD
2008年第11期1166-1167,共2页
Chinese Journal of Neuromedicine
关键词
伽玛刀
血管网状细胞瘤
儿童
Gamma knife radiosurgery
Hemangioblastoma
Children
