摘要
目的:建立高效液相色谱法对骨筋丸胶囊进行含量测定。方法:选用Hypersil ODS分析柱(250 mm×4.6 mm,5μm),乙腈-0.05 mol·L^(-1)磷酸二氢钠溶液(45:55),流速:1.0 ml·min^(-1);检测波长:440 nm。结果:血竭素高氯酸盐在0.14～1.40μg内线性关系良好(r=0.999 7),平均回收率为98.3%,RSD=0.7%(n=6)。结论:方法简便、快速、准确,能有效控制骨筋丸胶囊质量。
Objective ： To establish a HPLC method for the determination of dracorhodin perehlorate in Gujianwan Capsules. Method： Hypersil ODS C18 column（250 mm ×4.6 mm,5 μm） was used. The mobile phase was aeetonitrile -0.05 mol.L^-1 sodium dihydrogen phosphate solution （45：55 ） the flow rate was 1.0 ml.min^-1 ,the detection wavelength was 440 nm. Result： The linear range of dracorhodin perchlorate was 0.14 - 1.40 μg（ r = 0. 999 7 ）, the average recovery was 98.3%, RSD = 0.7% （ n = 6 ）. Conclusion： The method is simple, rapid and accurate. It can be used for quality control of Gujianwan Capsules.
出处
《中国药师》
CAS
2008年第11期1323-1325,共3页
China Pharmacist
