摘要
目的探讨脑利钠肽（brain natriuretic peptide，BNP）在不完全川崎病（incomplete Kawasaki disease，IKD）患儿中的变化及临床意义。方法确诊为急性期IKD患儿25例（急性期IKD组）。治疗2周后进入疾病恢复期20例，同期住院30例上呼吸道感染患儿作为对照组。测定并比较IKD患儿血浆BNP水平、外周血白细胞（WBC）计数和C-反应蛋白（CRP）水平。结果急性期IKD组BNP、WBC、CRP水平高于对照组（均P〈0．01）；20例IKD患儿急性期各指标水平均高于恢复期（均P〈0．01）。结论检测BNP有助于IKD患儿的早期诊断。
Objective To study the clinical significance of the changes of brain natriuretic peptide （ BNP） in children with incomplete Kawasaki disease （IKD）. Methods Of 25 cases of acute IKD,20 cases were at the recovery stage after 2 weeks treatment. 30 cases of upper respiratory tract infection at the same period were taken as controls. The plasma level of BNP,peripheral blood WBC count and C-reaction protein （CRP） levels were detected. Results BNP,WBC and CRP levels in acute IKD children were higher than that of control group （ P 〈 0.01 ）, which were higher in 20 cases of acute phase than in recovery phase （ P 〈 0.01 ）. Conclusion BNP contributes to the early diagnosis of IKD in children.
出处
《中国综合临床》
北大核心
2008年第11期1140-1141,共2页
Clinical Medicine of China
基金
河北省科技厅课题（07275527）
关键词
川崎病
脑利钠肽
C-反应蛋白
外周血白细胞
Kawasaki disease
Brain natriuretic peptide
C-reaction protein
peripheral blood leucocyte
