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糖尿病中的羰基应激及去羰基应激 被引量:1

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摘要 糖尿病慢性并发症是糖尿病致死致残的主要原因,严重影响糖尿病患者的生存质量。在糖尿病个体中很容易发生氧化应激及非酶糖基化,而氧化应激和非酶糖基化又可以进一步导致糖尿病并发症的发生发展。羰基应激理论将氧化应激和非酶糖基化有机地结合起来,认为在糖尿病个体处于羰基应激状态,在机体高血糖时尤其明显,它可以导致组织伤害以及全身血管的损害,体现为糖尿病并发症的发展。因此,去羰基应激作为治疗糖尿病及其并发症的一种新思路将有光明的发展前景。
作者 孟萌 沈志祥
出处 《牡丹江医学院学报》 2008年第5期62-64,共3页 Journal of Mudanjiang Medical University
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