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肝硬化患者凝血指标的变化及其临床意义 被引量:13

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摘要 目的研究肝硬化患者血浆凝血酶时间(TT),凝血酶原时间(PT),活化部分凝血酶原时间(APTT),纤维蛋白原(Fib)4项凝血指标的变化及其临床意义。方法用全自动血凝仪对肝硬化患者及健康对照组进行TT、PT、APTT、Fib的测定。结果与健康对照组比较,肝硬化患者TT、PT、APTT明显延长(P<0.01),Fib明显降低(P<0.01),随着肝功能损害程度的加重,其凝血功能障碍越明显。结论肝硬化患者血液处于明显的低凝状态,及时对此类患者检测凝血指标有利于了解肝硬化患者肝功能损害程度,预防继发性出血,指导临床诊疗。
作者 李媛媛
出处 《检验医学与临床》 CAS 2008年第20期1253-1254,共2页 Laboratory Medicine and Clinic
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