摘要
目的探讨肝硬化患者凝血功能变化及其与Child-Pugh肝功能分级的关系。方法测定47例肝硬化患者的凝血酶原时间(PT)、活化部分凝血酶原时间(APTT)和纤维蛋白原(FIB),同时设健康志愿者28名为对照组。结果肝硬化患者存在不同程度凝血功能障碍,PT、APTT、FIB水平与对照组有显著性差异(P<0.01);不同肝功能分级检测结果显示A、B、C级之间PT、APTT、FIB比较差异显著。结论肝硬化患者PT、APTT延长,FIB值降低且与疾病程度密切相关。
Objective To probe into the relationship of coagulation function to the Child-Pugh grades of liver function in the patients with hepatocirrhosis. Method The 47 patients with hepatocirrhosis at different course of the disease were selected to receive detection and 28 healthy people were chosen as control. The their indexes including PT, APTT and FIB were measured. Result The coagulation insufficiency existed in various degrees of all the patients with hepatocirrhosis. There were remarkably differences （P〈0.01） between the two groups with comparison of the values of PT, APTT and FIB. The values of PT APTT and FIB of grade A and B, grade B and C. Conclusion PT and APTT prolong and the content of FIB decrease in the patients with hepatoeirrhosis, these data are highly related to the degrees of the disease.
出处
《实用医药杂志》
2009年第9期14-15,共2页
Practical Journal of Medicine & Pharmacy
