摘要
目的检测女性冠状动脉粥样硬化性心脏病（冠心病）患者血清脂联素及体质指数，并探讨其与冠心病的关系。方法初步诊断为冠心病的女性患者125例，其中确诊冠心病患者50例为冠心病组，非冠心病患者75例为非冠心病组。分别测量2组身高、体重获取体质指数，同时抽取肘静脉血检测脂联素。结果冠心病组患者的年龄、体质指数高于非冠心病组患者，2组相比有统计学意义。年龄（66．83±10．59）对比（63．26±11．99），（P〈0．05）；体质指数（25．68±3．41）对比（23．30±8．47），（P〈0．01）。冠心病组脂联素水平低于非冠心病组，（7．59±2．44）对比（9．62±1．11），2组之间有统计学意义（P〈0．01）。结论女性冠心病患者的年龄、体质指数和脂联素与非冠心病患者相比存在差异，脂联素是女性冠心病患者的独立危险因素。
Objective To evaluate the relationship between plasma level of adiponectin, body mass index （BMI） and coronary artery disease in female patients. Methods One hundred and twenty-five female patients were enrolled. Coronary artery disease was determined by coronary angiography or indexed myocardial infarction. Body height and body mass were measured in the morning. BMI was calculated. Plasma level of adiponectin was also determined by ELLSA method. Results Age, BMI were higher in patients with coronary artery disease than those with non-coronary heart disease （ P 〈 0.05 ） , and adiponectin was lower in patients with coronary artery disease than those with non-coronary heart disease （P 〈 0. 01 ）. Logistic regression analysis showed adiponectin was the independent risk factor for coronary artery disease in females. Conclusion There were significant differences with respect to age and BMI between female patients with coronary artery disease and non- coronary artery disease. Adiponectin（ OR = 1.84） was the independent risk factor for coronary artery disease in females.
出处
《中国医药》
2008年第10期577-578,共2页
China Medicine
基金
河北省科技厅资助项目（072761133）
