摘要
目的:观察西米替丁、叶酸、普鲁卡因保留灌肠治疗婴幼儿轮状病毒性肠炎的疗效。方法:81例轮状病毒性肠炎患儿随机分为对照组38例,药物保留灌肠组43例,药物保留灌肠组在对照组常规治疗基础上等渗温盐水清洁灌肠后予以西米替丁10 mg/(kg.次)+叶酸5 mg/(kg.次)+2%普鲁卡因0.2 mL/(kg.次)保留灌肠,2次/d,观察各组发热、呕吐、腹泻、脱水等临床表现消失和腹泻总病程时间,并比较疗效。结果:治疗72 h后,对照组、药物保留灌肠组总有效率分别为81.58%、96.67%,药物保留灌肠组高于对照组(χ2=4.202,P<0.05),在退热、止吐、止泻、脱水纠正时间及总病程,药物保留灌肠组较对照组明显缩短。结论:在常规治疗基础上,配合药物保留灌肠治疗婴幼儿轮状病毒性肠炎可较快缓解病情,缩短疗程。
Objective：To observe the effect of the treatment of infantile rotavirus enteritis with cimetidine, folic acid, procaine retention enema. Methods： 81 cases of rotavirus enteritis were randomly divided into two groups, 38 cases were in the control group, 43 cases were in the drug retention enema group. In addition to the enema with isotonic saline-cleaning, drug retention enema group were treated with cimetidine ＋ Folic acid ＋ 2% procaine retention enema, twice a day and the duration of fever, vomiting, diarrhea, dehydration were observed with the efficacy compared with that of the control group. Results： After 72 hours of the treatment, the total efficiency of the control group and the drug retention enema group was 81.58% and 96.67% respectively （Х^2 = 4.202, P 〈 0.05 ）. The drug retention enema group was significantly shorter than the control group in the time of pyretolysis, vomiting stopping, diarrhea stopping, dehydration correcting and the course of disease. Conclusions： Based on the conventional treatment, the treatment with drug retention enema in infantile rotavirus enteritis can ease the disease and shorten the course of treatment.
出处
《儿科药学杂志》
CAS
2008年第5期48-50,共3页
Journal of Pediatric Pharmacy
