摘要
多数功能磁共振成像(fMRI)研究是在特定的实验任务条件下对大脑的活动进行分析。然而,大脑在静息状态下仍存在自发神经元活动,这些自发活动具有较强的低频同步性,对于静息状态下的大脑活动的研究有利于全面认识大脑的内在活动机制。本文主要综述目前静息状态脑功能连接fMRI常用分析方法及其在临床疾病中的初步应用。
Most of functional magnetic resonance imaging（fMRI）studies have employed task-related paradigm to explore brain response to an external stimulus.However,the brain is very active in the absence of any specific experimental tasks and the spontaneous activity exhibits coherent low-frequency synchrony.Studies on resting-state brain activity have provided insight into the intrinsic activity mechanism of the brain.In this study we review recent popular methods on resting-state functional connectivity and their preliminary applications to clinical diseases.
出处
《中国医学影像技术》
CSCD
北大核心
2008年第8期1277-1280,共4页
Chinese Journal of Medical Imaging Technology
基金
国家自然科学基金资助项目(30500130)
关键词
磁共振成像
脑
Magnetic resonance imaging
Brain
